.: Дата публікації 2009-07-02 :: Переглядів: 8 :: 
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Diagnostic significance of C-reactive protein as a marker of aseptic inflammation during the acute period of cerebral concussion
O.V. TKACHENKO, A.V. TKACHEV
Purpose – to study the peculiarities of S-reactive protein content in blood and liquor in patients in the acute period of cerebral concussion.
Methods and subjects. The examination of 22 patients with the closed cerebral injury at the age 17–54 years (the average age – 27.6 ± 0.4). There were 6 women (27.2 %), 16 men (72.8 %). The examination of the C-reactive protein level content in blood and liquor was carried out during the first days after the injury (first group – 8 persons), during the 2–4 days (second group – 7), during the 5 days and later (third group – 7).
Results. There was no marked difference of C-reactive protein level content between all three groups of patients (р > 0.05). However, it was found out the significant statistic rise of this index comparing with the screening group (р < 0.01). The tendency of the dependence of C-reactive protein level decrease on the prescription of the
cerebral injury was determined. There was marked correlation of C-reactive protein level content changes in blood and liquor.
Conclusions. Patients in the acute period of cerebral concussion had increased level of C-reactive protein content in blood and liquor. The increased level of C-reactive protein persists longer in liquor than in blood. It can be considered as an indirect marker of the development and the course of an accompanied reparative reaction as aseptic inflammation.
Ключові слова: cerebral concussion, C-reactive protein, blood, liquor.
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