.: Дата публікації 2009-11-17 :: Переглядів: 11 :: 
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C-reactive protein: correlation with triennial frequency relapses in patients with ischemic stroke against the background of arterial hypertension
O.L. MARKULAN
Purpose: to study the influence of arterial hypertension (AH) and adherence to antihypertensive therapy for the
triennial consequences of atherothrombotic stroke according to C-reactive protein level (C-RP).
Methods and subjects. 151 patients with stroke of 3 years duration of atherothrombotic genesis were examined.
Clinical, neurological and instrumental examinations, general and biochemical blood test, coagulogram, MRI, cerebral helical computer tomography, cerebral vessels duplex scanning, heart vessels ultrasound examination and
echocardioscopy were carried out.
Results. 60.9 % patients suffered from AH. The triennial frequency of repeated ischemic stroke and lethal outcomes following IS was higher in patients with AH. The frequency of strokes relapses in patients with AH against the background of hypotensive medications therapy was less comparing with those patients who were not treated
against AH. Patients who underwent the hypotensive therapy demonstrated different C-RP level depending on
relapse occurrence. In case of relapse its level was high.
Conclusions. The efficacy of antihypertensive therapy related to the secondary stroke prevention reduces in
case of high C-RP level. It requires C-RP level estimation to determine the stroke relapse risk group and it is aimed to improve anti inflammation therapy.
Ключові слова: atherothrombotic subtype, stroke relapse, C-reactive protein, antihypertensive therapy, arterial
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